Brent's take:
This is basically the flat-pole piece version of the SSL-5. On the current Seymour Duncan site they claim a slight output boost for this pickup vs. the SSL-5, but I imagine that is comparing the two on the same guitar, which isn't quite apples to apples as you would normally use the SSL-6 on a guitar with a flatter fingerboard and the SSL-5 on a guitar with a smaller-radiused fingerboard (generally a vintage or vintage-styled guitar).
From the manufacturer:
"application
Beefed up true single-coil for warm instruments. Perfect for Texas blues rock, classic rock and heavy rock.
description
Beefed up true single-coil for warm instruments. Perfect for Texas blues rock, classic rock and heavy rock.
complete setup
Calibrated set available with RW/RP middle pickup. Many players use an SSL-6 in the bridge position with vintage output pickups, like SSL-2's, in the neck and middle for tonal versatility.
guitars
For heavier and brighter-toned instruments with ash or alder bodies. Works well with maple or rosewood fingerboards.
available mods
Reverse wound, reverse polarity (RW/RP) middle pickups for hum-canceling in positions "2" and "4" on the five-way switch.
specs
Magnet type: alnico 5 rods, D.C. Resistance 12.9k
players
Duke Robillard, Mark Slaughter / Slaughter, Rafa Payan / Juan Luis Guerra"
Best videos/sound clips:
Johnny Hawthorne here is playing an SSL-6 in the bridge position of a Fender Select Strat. Some great mid-gain tones here - sounds like "Summer of '69" - not too bright...good crunch... He starts playing at 0:54.
Basic video below put out by Seymour Duncan showing the SSL-6 off in the bridge position of a Fender Strat (looks to be a MIM but I can't be sure). The player is John Patelis, and the amp he is using appears to be a Soldano Astroverb 16 1x12 combo.
Another SD video here; on this one the player is Nick Johnston. Nick is playing a Schecter guitar through an Apollo Twin audio interface with the SSL-6 in the bridge and the Alnico II Pros (APS-2) in the neck and middle positions. The song he's playing at first has almost a gypsy-like flair and the tones are mid-gain. He then switches at 3:07 to a cleaner tone with no backing track and does a good job showing how you can switch from clean to a lead tone by modulating the guitar's volume.
Sean Rock recorded this video of his G&L Legacy with a newly installed SSL-6 in the bridge. He goes for some more modern tones than the players above so I thought I'd include this video. As a side note he talks until 6:20 so I'd recommend skipping ahead to the playing.
Here's an odd setup that is well-mic'd: an SSL-5 in the bridge with a SSL-6 in the neck. The use of an SSL-5 or 6 in the neck or middle position is definitely more atypical, so I wanted to include this video. He also has a switch that allows for the neck+bridge combo to be played. Basic strummed chords used to show the tones. Guitar used is a Fender Highway 1 strat with a 1999 MIM neck. Amp used is the Silverface Fender Champ with a Jensen C8R speaker, and the setup is mic'd with a shure sm57. Player is Ed Migliaccio.